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Newcases have been rising steadily for more than a month now in the United States, urging at least 22 state governments to pause or roll back their opening plans in an attempt to limit the emergence of a . According to the World Health Organization, the fastest way to end a pandemic is through a vaccine. For people around the world who are tired of it , and that , it can not come soon enough.
How far away is a vaccine against COVID-19? Maybe not as far as you think. In fact, on Wednesday, the US government promised to buy 100 million doses for $ 1.95 billion from Pfizer when it receives the final approval from the Food and Drug Administration for a vaccine it is developing. This comes on the heels of several similar offers between the United States and other drug manufacturers. Several experimental coronavirus vaccine trials, including Pfizers, are already taking place in the United States, in coordination with the National Institute of Allergy and Infectious Diseases.
Vaccines can take decades to develop and distribute globally. But there have never been so many doctors and researchers who worked hard and fast on one. Just seven months ago, the virus that causes COVID-19, was first detected, 23 vaccine candidates are already in human trials, with 130 more still evolving. Here’s what’s happening now.
As a relatively new disease, much remains unknown about COVID-19. This article is frequently updated and is intended to be a general overview, not a source of medical advice. If you are looking for more information on coronavirus testing,close to you. here is and .
Latest COVID-19 vaccine news
- Five large companies promised that the vaccines they develop will be safe, effective and created without cutting corners. AstraZeneca, Johnson & Johnson, Merck, Moderna and Pfizer agreed to the promises.
- An experimental coronavirus vaccine has triggered an immune response in healthy human volunteers, researchers at Oxford University reported. The vaccine may be ready in September.
- The Chinese military has already been approved to use a CanSino vaccine candidate that has also been shown to elicit an immune response.
- The European Union could approve a coronavirus vaccine before the end of 2020, its chief vaccine minister Marco Cavaleri told Bloomberg.
- Over 138,000 people in the United States has volunteered for COVID-19 vaccine testing as of July 20, but more is still needed, USA Today reported.
- Vaccines must work at least 50% better than a placebo to prevent COVID-19 from being approved, according to minimum standards set by the FDA.
Will there just be one vaccine for everyone?
We probably won’t know until next year, but America’s top disease expert, Dr. Anthony Fauci, has suggested that it may take several different vaccines manufactured and distributed by different laboratories to end the pandemic, in a paper published May 11 in the journal. Science.
The COVID vaccine is developing faster
Vaccines usually take about 10 to 15 years to develop and approve through four phases that include human trials. But an FDA rapid detection process and a coronavirus vaccine working group called Operation Warp Speed are accelerating development.
For example, instead of submitting all sections of the application after all four phases have been completed, approved vaccine projects can submit data to the FDA bit by bit.
At the same time, Operation Warp Speed is financial support to begin manufacturing doses while clinical trials are still ongoing. This means that if and when these vaccines are approved, there is already a stock of doses ready to be distributed nationally. Because of this, Fauci said he expects the United States to have “hundreds of millions of doses” of the vaccine ready for distribution in early 2021.
Promising vaccines against coronavirus from the UK, USA, China
Here’s a quick look at some of the frontrunners in the race to find a vaccine against COVID-19, including where the vaccines are being developed, where they are testing them and when researchers believe they may be ready for widespread distribution, if known.
Oxford University / AstraZeneca (UK): It is currently testing its vaccine on 100,000 human volunteers in at least three countries. Leading researcher Dr. Sarah Gilbert has said that they are aiming for a release in the autumn of 2020. As mentioned above, the latest results show that the vaccine triggers an immune response.
Modern (US): An apparent mix of state regulators has delayed large-scale human testing, which will now begin in late July. Modernes CEO has told Barrons that he expects the company to know by Thanksgiving if the vaccine is safe and effective and should be able to distribute it in early 2021 if it is.
Pfizer (USA): Although its four COVID-19 vaccine candidates are still in early-stage human studies, two of them have been rapidly detected by the FDA. Pfizer’s chief business officer told the US Congress that the company may be ready to apply for FDA approval in October.
SinoVac (China): It is currently testing its vaccine against about 10,000 human volunteers in China and about 9,000 in Brazil and will soon begin testing on about 1,900 test subjects in Indonesia. The CEO of BioPharma, SinoVac’s Indonesian partner, has said he expects the vaccine to be ready in early 2021.
SinoPharm (China): Currently testing about 15,000 volunteers in the Middle East in a trial that the state-owned company expects to last for three to six months. SinoPharm recently built a second plant to manufacture the vaccine and doubled its capacity to approximately 200 million doses per year.
CanSino Biologics (China): To begin major human trials this summer, CanSino’s vaccine has already been approved by the Chinese military.
What happens if we never find a coronavirus vaccine?
Coronavirus is a large class of viruses and so far there are no vaccines for any of them. Although there are promising early results, there is no guarantee of a vaccine until 2021. Statistically, only about 6% of vaccine candidates have ever reached the market, according to a Reuters special report.
Early evidence suggests that the coronavirus does not appear to mutate as rapidly or frequently as the flu, and it is believed that the virus has not yet been mutated enough to interfere with vaccine development – although our knowledge may change.
The further we go without a vaccine, the more likely the focus will change towards treatments, for example, which reportedly showed promising results, and , a steroid that doctors say increases the survival rate among the most serious cases. With effective therapeutic treatments, many viruses that used to be lethal are no longer death sentences. Patients with HIV, for example, can now expect to have the same life expectancy as non-HIV-positive individuals thanks to tremendous advances in treatment.
Locking measures are already in placeeven if it has a potential , cities may reverse certain quarantine measures, including requirements and . Eventually, the global population can reach the 60% to 70% required for to protect those who are not immune.